Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Azoxystrobin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azoxystrobin SCHEMBL29362394 | 0.94 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL4447188 | 0.94 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL18823 | 0.94 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL4113006 | 0.94 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL55087 | 0.94 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL17701154 | 0.93 | MAP4K4 (0.38) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL17701140 | 0.92 | PIN1 (0.37) | PIN1MAP4K4ALDH1A1HPGDTSHR | |
| Azoxystrobin SCHEMBL5902501 | 0.88 | PIN1 (0.37) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL17701168 | 0.88 | SYK (0.37) | PIN1MAP4K4SCN9AALDH1A1HPGD | |
| Azoxystrobin SCHEMBL19356835 | 0.86 | PIN1 (0.36) | PIN1MAP4K4SCN9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565057-A2 | FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT | ISAGRO S.p.A. (IT) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004047540-A2 | FUNGICIDAL COMPOSITIONS CONTAINING AT LEAST ONE SALT OF PHOSPHOROUS ACID AND AT LEAST A SECOND FUNGICIDAL COMPONENT | ISAGRO S.P.A. (IT) | 2004-06-10 | — | — | WO | disclosed |