Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44594 | 0.92 | HTR1A (0.39) | HDAC4HDAC1HDAC6KMT2ACAMK2D | |
| SCHEMBL44314 | 0.89 | HDAC4 (0.42) | HPGDHDAC4HDAC6ALDH1A1 | |
| SCHEMBL44565 | 0.88 | HPGD (0.51) | HPGDTSHRHDAC4HDAC6KMT2A | |
| SCHEMBL44472 | 0.87 | HTT (0.40) | TSHRHDAC1KMT2A | |
| SCHEMBL38209 | 0.86 | GSK3B (0.43) | FYNHDAC4HDAC1HDAC6CAMK2D | |
| SCHEMBL994121 | 0.85 | LMNA (0.46) | TSHRKMT2AALDH1A1 | |
| SCHEMBL46482 | 0.82 | FYN (0.34) | FYNHDAC4HDAC1HDAC6CAMK2D | |
| SCHEMBL44623 | 0.82 | FFAR1 (0.42) | TSHRKMT2AALDH1A1 | |
| SCHEMBL44354 | 0.82 | HPGD (0.45) | HPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL45433 | 0.81 | GLA (0.37) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |