Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584520 | 0.82 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL13168423 | 0.82 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL3584527 | 0.82 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL4437695 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL3593210 | 0.74 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL3593214 | 0.74 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL3593208 | 0.74 | ALDH1A1 (0.37) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL4437703 | 0.72 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 | |
| SCHEMBL4435442 | 0.71 | DRD2 (0.35) | GAAMAPTMAPK1CA12CA1 | |
| SCHEMBL3582511 | 0.71 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121598-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076754-A2 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-06-26 | — | — | WO | disclosed |