Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HBB | P68871 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448156 | 1.00 | APP (0.68) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4454503 | 0.98 | APP (0.71) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4454499 | 0.98 | APP (0.71) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL75061 | 0.92 | APP (0.62) | APPMAPTRELAHSD17B3PTGS1 | |
| SCHEMBL75060 | 0.92 | APP (0.62) | APPMAPTRELAHSD17B3PTGS1 | |
| SCHEMBL12446433 | 0.85 | TLR9 (0.58) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1821464 | 0.85 | TLR9 (0.58) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9369 | 0.84 | ALDH1A1 (0.58) | MAPTHBBALOX15ALDH1A1 | |
| SCHEMBL11876857 | 0.84 | APP (0.95) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9017239 | 0.84 | APP (0.95) | APPHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635595-B2 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R | 2009-12-22 | — | — | US | disclosed |
| US-20050158245-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2005-07-21 | — | — | US | disclosed |
| US-20040087842-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158245-A1 | Fluorescent probes for saccharrides | H1-3, H1-0, H1-2 | APP 4847/4885HDAC3 110/4885HDAC4 271/4885 |
| US-20040087842-A1 | Fluorescent probes for saccharrides | ST6GAL1, SLC5A1, CA6 | APP 4844/4885HDAC3 771/4885HDAC4 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.