Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | HBB | P68871 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75061 | 1.00 | APP (0.62) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL4448156 | 0.92 | APP (0.68) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL4448158 | 0.92 | APP (0.68) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL4454503 | 0.91 | APP (0.71) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL4454499 | 0.91 | APP (0.71) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL9369 | 0.87 | ALDH1A1 (0.58) | MAPTHBBALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL18641492 | 0.85 | TSHR (0.55) | MAPTHBBALOX15ALDH1A1 | |
| SCHEMBL22594932 | 0.84 | PTGS1 (0.57) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL1714446 | 0.82 | RELA (0.81) | APPRELAPTGS1MAPTMEN1 | |
| SCHEMBL7915381 | 0.82 | RELA (0.81) | APPRELAPTGS1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150176-B1 | IMPLANTABLE CONCENTRATION SENSOR AND DEVICE | ST JUDE MEDICAL (SE) | 2016-04-27 | — | — | EP | disclosed |
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569502-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | Geddes, Chris (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | GEDDES, CHRIS, DR. | 2013-08-15 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338602-B2 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8131333-B2 | Ophthalmic sensor | EYESENSE AG (CH) | 2012-03-06 | — | — | US | disclosed |
| EP-1671118-B1 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIV MARYLAND (US) | 2011-11-02 | — | — | EP | disclosed |
| EP-1644330-B1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIV MARYLAND (US) | 2011-08-17 | — | — | EP | disclosed |
| US-20070030443-A1 | Opthalmic sensor | EYESENSE AG (CH) | 2007-02-08 | — | — | US | disclosed |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | GEDDES, CHRIS, DR. | 2007-01-25 | — | — | US | disclosed |
| EP-1671118-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | University of Maryland Biotechnology Institute (US) | 2006-06-21 | — | — | EP | disclosed |
| EP-1654543-A1 | OPHTHALMIC SENSOR | Novartis AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| EP-1644330-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050158245-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005029033-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2005015237-A1 | OPHTHALMIC SENSOR | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| WO-2005000109-A2 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040087842-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158245-A1 | Fluorescent probes for saccharrides | H1-3, H1-0, H1-2 | APP 4847/4885RELA 539/4885PTGS1 3967/4885 |
| US-20130210158-A1 | QUATERNARY NITROGEN HETEROCYCLIC COMPOUNDS FOR DETECTING AQUEOUS MONOSACCHARIDES IN PHYSIOLOGICAL FLUIDS | SLC5A1, NISCH, SLC5A2 | APP 3845/4885RELA 451/4885PTGS1 3825/4885 |
| US-20040087842-A1 | Fluorescent probes for saccharrides | ST6GAL1, SLC5A1, CA6 | APP 4844/4885RELA 985/4885PTGS1 2949/4885 |
| US-20070020182-A1 | Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids | SLC5A1, NISCH, SLC5A2 | APP 3845/4885RELA 451/4885PTGS1 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.