Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29057317 | 0.92 | ALDH1A1 (0.39) | LMNAHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL9619709 | 0.88 | MEN1 (0.44) | LMNAHPGDALDH1A1USP2HTT | |
| SCHEMBL5068796 | 0.84 | LMNA (0.38) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL9386897 | 0.83 | LMNA (0.37) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL2188576 | 0.80 | KMT2A (0.39) | SMN1; SMN2ALDH1A1NPSR1HTTMAPT | |
| SCHEMBL1723173 | 0.77 | ATM (0.40) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL19179591 | 0.76 | ALDH1A1 (0.41) | LMNAHPGDSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL4959091 | 0.76 | ALDH1A1 (0.41) | LMNAHPGDSMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL993046 | 0.75 | ALDH1A1 (0.43) | LMNAHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL136599 | 0.75 | ALDH1A1 (0.43) | LMNAHPGDSMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466771-A | Polymeric materials | VICTREX MFG LTD (GB) | 2009-06-24 | — | — | CN | disclosed |
| CN-101466770-A | Polymeric materials | VICTREX MFG LTD (GB) | 2009-06-24 | — | — | CN | disclosed |
| EP-2027181-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007144610-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |