Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814885 | 0.81 | LMNA (0.35) | SMN1; SMN2HPGDLMNAALPGITGB1 | |
| SCHEMBL5068796 | 0.77 | LMNA (0.38) | TDP1SMN1; SMN2HPGDLMNAALPG | |
| SCHEMBL4448703 | 0.77 | LMNA (0.38) | TDP1SMN1; SMN2HPGDLMNAALPG | |
| SCHEMBL9386897 | 0.76 | LMNA (0.37) | TDP1SMN1; SMN2HPGDLMNAALPG | |
| SCHEMBL17950520 | 0.73 | ATM (0.75) | ATMTDP1L3MBTL1CTSLCTSK | |
| SCHEMBL5880322 | 0.72 | L3MBTL1 (0.47) | ATMTDP1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL209624 | 0.70 | ATM (0.67) | ATMTDP1L3MBTL1CTSLCTSK | |
| SCHEMBL2454243 | 0.70 | ALDH1A1 (0.41) | ATMTDP1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL993046 | 0.69 | ALDH1A1 (0.43) | ATMTDP1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL29034394 | 0.69 | ALDH1A1 (0.39) | ATMTDP1L3MBTL1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20160145385-A1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2016-05-26 | — | — | US | disclosed |
| US-9175136-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2344565-B1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY SPECIALTY POLYMERS USA (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20110213095-A1 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-09-01 | — | — | US | disclosed |
| EP-2344565-A1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | Solvay Advanced Polymers, L.L.C. (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2342261-A1 | IMPROVED METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S AND IMPROVED METHOD FOR PROVIDING A SODIUM CARBONATE SUITABLE FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S | Solvay Advanced Polymers, L.L.C. (US) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010046484-A1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046487-A1 | IMPROVED METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S AND IMPROVED METHOD FOR PROVIDING A SODIUM CARBONATE SUITABLE FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | PKM, KCNK10, KCNK9 | ATM 1110/4885TDP1 3884/4885L3MBTL1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.