SCHEMBL4448730

SCHEMBL4448730

CCc1cccc(P(=O)(O)Oc2ccccc2C)c1CC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 3/20 0.35
NPC1 O15118 2/20 0.35
PTK2B Q14289 2/20 0.35
RAB9A P51151 1/20 0.34
NOTUM Q6P988 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
ALPG P10696 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4460850 0.90 ALDH1A1 (0.40) ALDH1A1MAPTPOLBNPC1PTK2B
SCHEMBL4454064 0.89 ALDH1A1 (0.38) ALDH1A1MAPTKDM4EKMT2APOLB
SCHEMBL4451201 0.85 LTB4R (0.37) ALDH1A1MAPTKDM4EPOLBNPC1
SCHEMBL4449871 0.85 LTB4R (0.39) ALDH1A1POLBNPC1PTK2BRAB9A
SCHEMBL4453965 0.84 ALOX5 (0.38) ALDH1A1POLBNPC1PTK2B
SCHEMBL4458102 0.84 ALDH1A1 (0.40) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL4462346 0.83 THRA (0.40) ALDH1A1POLBNPC1PTK2B
SCHEMBL3888421 0.82 ALDH1A1 (0.41) ALDH1A1MAPTKDM4EKMT2APOLB
SCHEMBL4452100 0.82 MAPT (0.43) ALDH1A1MAPTPOLBNPC1PTK2B
SCHEMBL4451713 0.82 MAPT (0.50) ALDH1A1MAPTKMT2APOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed