Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447575 | 0.86 | — | — | |
| SCHEMBL3214638 | 0.82 | MAPK1 (0.53) | LDHALMNAHTTNPC1SMN1; SMN2 | |
| SCHEMBL3209730 | 0.79 | LMNA (0.49) | LMNAHTTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL3198917 | 0.78 | CALM1 (0.45) | LDHAKDM4EATM | |
| SCHEMBL3209344 | 0.78 | CYP19A1 (0.50) | KDM4EATMMAPTGAA | |
| SCHEMBL27936118 | 0.78 | SMN1; SMN2 (0.54) | LMNAHTTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL28033799 | 0.77 | TNKS2 (0.46) | LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL17876786 | 0.77 | BRD4 (0.44) | LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3201528 | 0.76 | ALDH1A1 (0.44) | KMT2AKDM4EATMALDH1A1MAPT | |
| SCHEMBL13486187 | 0.75 | ALDH1A1 (0.52) | LMNAHTTNPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500999-B | Hydroxyphenyl derivatives and biological applications thereof | FAB PHARMA S A S | 2014-01-15 | — | — | CN | disclosed |
| EP-2010495-A2 | NEW HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | Mutabilis SA (FR) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007135562-A2 | HYDROXYPHENYL DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS S.A. (FR) | 2007-11-29 | — | — | WO | disclosed |