Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177295 | 0.87 | CYP4F2 (0.55) | TNKS2PRSS1TMPRSS15HTTLMNA | |
| SCHEMBL21110506 | 0.86 | FAAH (0.43) | TNKS2HTTKDM4EMITFALDH1A1 | |
| SCHEMBL27673408 | 0.85 | HTT (0.42) | PRSS1TMPRSS15HTTLMNAKDM4E | |
| SCHEMBL10435324 | 0.85 | CYP4F2 (0.57) | HTTKDM4EMITFALDH1A1FAAH | |
| SCHEMBL28069749 | 0.83 | HTT (0.41) | PRSS1TMPRSS15HTTLMNAKDM4E | |
| SCHEMBL27460564 | 0.81 | HTT (0.39) | PRSS1TMPRSS15HTTLMNAKDM4E | |
| SCHEMBL15161497 | 0.78 | PKM (0.57) | HTTLMNAKDM4E | |
| SCHEMBL4447575 | 0.78 | — | — | |
| SCHEMBL27984901 | 0.77 | MRGPRX4 (0.44) | HTTLMNAALDH1A1 | |
| SCHEMBL4448874 | 0.77 | LDHA (0.44) | HTTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-109574927-A | N- (substituted sulphonyl) benzamide derivatives and preparation method thereof and medical usage | 浙江海正药业股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |