Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19056256 | 0.90 | ALDH1A1 (0.31) | ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4268434 | 0.76 | MAPK1 (0.32) | ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL911083 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL23499500 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL29960878 | 0.74 | — | — | |
| SCHEMBL28849090 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL3627628 | 0.72 | GPR3 (0.34) | — | |
| SCHEMBL28806317 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| SCHEMBL28303653 | 0.72 | BACE1 (0.38) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| SCHEMBL6762451 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPK1PTPN1PTPRCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118223194-A | Soft and durable nonwoven web | 金伯利-克拉克环球有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116728919-A | Laterally extensible nonwoven composites | 金伯利-克拉克环球有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-106459246-B | Process for producing olefin polymer, catalyst for olefin polymerization, and olefin polymer | 出光兴产株式会社 | 2020-04-10 | — | — | CN | disclosed |
| CN-105722485-B | Absorbent article comprising a soft and durable backsheet | 金伯利-克拉克环球有限公司 | 2020-02-11 | — | — | CN | disclosed |
| EP-1865006-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |