Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849090 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| SCHEMBL28806317 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| SCHEMBL28303653 | 0.73 | BACE1 (0.38) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL19056255 | 0.72 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL29281412 | 0.72 | ALDH1A1 (0.35) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| SCHEMBL6762451 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL911069 | 0.71 | GPR3 (0.35) | — | |
| SCHEMBL28149503 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL9066989 | 0.71 | CYP2A6 (0.31) | ALDH1A1MAPK1PTPN1PTPRCPTPRF | |
| Hydrochloric Acid SCHEMBL19056256 | 0.69 | ALDH1A1 (0.31) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650964-B | Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-111757887-B | 1, 2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-110650965-B | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-110650978-B | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114901732-A | Machine direction oriented polyethylene film | 埃克森美孚化学专利公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114787250-A | Biaxially oriented polyethylene film and method for producing the same | 埃克森美孚化学专利公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114787249-A | Biaxially oriented polyethylene film | 埃克森美孚化学专利公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-111757887-A | 1, 2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-110650964-A | Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110650965-A | Dihydrocarbyl-silyl-bridged-1, 3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-104822716-A | BRANCHED POLYETHYLENE WITH IMPROVED PROCESSING AND HIGH TEAR FILMS MADE THEREFROM | EXXONMOBIL CHEM PATENTS INC | 2015-08-05 | — | — | CN | disclosed |
| US-8507604-B2 | Polyolefin graft copolymer and adhesive composition | IDEMITSU KOSAN CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| EP-1867662-B2 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-20110015338-A1 | POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION | IDEMITSU KOSAN CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20100324242-A1 | HIGHLY PURE, TERMINAL-UNSATURATED OLEFIN POLYMER AND PROCESS FOR PRODUCTION THEREOF | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2253648-A1 | POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-2241582-A1 | AQUEOUS DISPERSION CONTAINING POLYOLEFIN GRAFT COPOLYMER | Idemitsu Kosan Co., Ltd. (JP) | 2010-10-20 | — | — | EP | disclosed |
| EP-1867662-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1865007-B1 | Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same | IDEMITSU KOSAN CO (JP) | 2009-03-25 | — | — | EP | disclosed |
| CN-1226894-A | Metallocene and olefin polymerization catalyst | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-08-25 | — | — | CN | disclosed |