SCHEMBL4449146

SCHEMBL4449146

O=C(O)c1ccc(C(=O)O)c(COc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 7/20 0.56
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
NR4A1 P22736 2/20 0.56
NR4A3 Q92570 2/20 0.56
PKM P14618 1/20 0.54
MAP4K4 O95819 1/20 0.53
PTPRC P08575 1/20 0.53
PTPN1 P18031 1/20 0.53
SRD5A2 P31213 2/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
MRGPRX4 Q96LA9 1/20 0.49
PLA2G4B P0C869 1/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
HPGD P15428 1/20 0.48
GPBAR1 Q8TDU6 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9845266 0.93 NR4A2 (0.56) NR4A2NPC1RAB9ANR4A1NR4A3
SCHEMBL11328385 0.84 PKM (0.60) NR4A2RAB9ANR4A1NR4A3PKM
SCHEMBL1721145 0.84 NR4A2 (0.51) NR4A2NPC1RAB9AMAP4K4MRGPRX4
SCHEMBL13870505 0.84 TP53 (0.48) NR4A2NPC1RAB9AMEN1KMT2A
SCHEMBL13870464 0.84 MRGPRX4 (0.59) NR4A2NPC1RAB9ANR4A1NR4A3
SCHEMBL9127513 0.84 MRGPRX4 (0.51) NR4A2NPC1RAB9APTPRCPTPN1
SCHEMBL1368181 0.82 TP53 (0.63) NR4A2NPC1RAB9ANR4A1NR4A3
SCHEMBL8890296 0.81 ALDH1A1 (0.61) NPC1RAB9APKMMEN1KMT2A
SCHEMBL38659231 0.81 NR4A2 (0.71) NR4A2NPC1RAB9ANR4A1NR4A3
SCHEMBL14966650 0.81 MAOB (0.61) NR4A2NPC1RAB9ANR4A1NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090136671-A1 Novel polyimide copolymer and metal laminate using the same NIPPON MEKTRON LIMITED (JP) 2009-05-28 US claimed