Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099347 | 0.86 | KMT2A (0.72) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL28091856 | 0.85 | KMT2A (0.65) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL9580710 | 0.82 | KMT2A (1.00) | KMT2AGAAHTTCA2CA5A | |
| Dinitrophenylene SCHEMBL30600045 | 0.80 | TSHR (0.94) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL205255 | 0.80 | KMT2A (0.75) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL6525363 | 0.78 | KMT2A (0.72) | KMT2AGAAHTTCA2CA5A | |
| Potassium Ion SCHEMBL10474224 | 0.78 | KMT2A (0.72) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL1148409 | 0.78 | KMT2A (0.72) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL189037 | 0.78 | CA2 (1.00) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL9471995 | 0.78 | KMT2A (0.72) | KMT2AGAAHTTCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541008-B2 | Fluid reactor | UNIVERSITY OF DURHAM OF UNIVERSITY OFFICE (GB) | 2009-06-02 | — | — | US | disclosed |
| US-7541008-B2 | Fluid reactor | UNIVERSITY OF DURHAM OF UNIVERSITY OFFICE (GB) | 2009-06-02 | — | — | US | disclosed |
| US-20050214184-A1 | Fluid reactor | UNIVERSITY OF DURHAM OF UNIVERSITY OFFICE (GB) | 2005-09-29 | — | — | US | disclosed |
| WO-2003095086-A2 | FLUID REACTOR | THE UNIVERSITY OF DURHAM (GB) | 2003-11-20 | — | — | WO | disclosed |