SCHEMBL8099347

SCHEMBL8099347

O=[N+]([O-])c1cccc(S(=O)(=O)F)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.72
GAA P10253 1/20 0.72
HTT P42858 1/20 0.72
CA2 P00918 3/20 0.68
CA5A P35218 1/20 0.68
MMP2 P08253 2/20 0.62
CA1 P00915 1/20 0.62
MMP1 P03956 1/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
MMP13 P45452 1/20 0.62
MEN1 O00255 2/20 0.60
LMNA P02545 2/20 0.59
TSHR P16473 1/20 0.59
F2 P00734 2/20 0.57
PRSS1 P07477 2/20 0.57
PRSS2 P07478 2/20 0.57
PRSS3 P35030 2/20 0.57
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449158 0.86 KMT2A (0.69) KMT2AGAAHTTCA2CA5A
SCHEMBL9580710 0.84 KMT2A (1.00) KMT2AGAAHTTCA2CA5A
SCHEMBL28091856 0.83 KMT2A (0.65) KMT2AGAAHTTCA2CA5A
SCHEMBL205255 0.82 KMT2A (0.75) KMT2AGAAHTTCA2CA5A
SCHEMBL189037 0.81 CA2 (1.00) KMT2AGAAHTTCA2CA5A
Potassium Ion SCHEMBL10474224 0.81 KMT2A (0.72) KMT2AGAAHTTCA2CA5A
SCHEMBL1148409 0.81 KMT2A (0.72) KMT2AGAAHTTCA2CA5A
SCHEMBL6525363 0.81 KMT2A (0.72) KMT2AGAAHTTCA2CA5A
SCHEMBL9471995 0.81 KMT2A (0.72) KMT2AGAAHTTCA2CA5A
SCHEMBL5899427 0.81 KMT2A (0.72) KMT2AGAAHTTCA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113603619-A Method for preparing aryl sulfonyl fluoride by taking aryl hydrazine hydrochloride as raw material 上海应用技术大学 2021-11-05 CN claimed
EP-2866029-A1 METHOD FOR PREPARING SAMPLE CONTAINING PANCREATIC JUICE COMPONENT, AND KIT FOR STORING BIOLOGICAL SAMPLE CONTAINING PANCREATIC JUICE COMPONENT AT ROOM TEMPERATURE Olympus Corporation (JP) 2015-04-29 EP claimed
EP-2757151-A1 METHOD FOR INHIBITING PROTEASE IN BIOLOGICAL SAMPLE CONTAINING PANCREATIC JUICE COMPONENT Olympus Corporation (JP) 2014-07-23 EP claimed
US-20140186869-A1 METHOD FOR INHIBITING PROTEASE IN BIOLOGICAL SAMPLE CONTAINING PANCREATIC JUICE COMPONENTS OLYMPUS CORPORATION (JP) 2014-07-03 US claimed
JP-3034937-A None JP disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
EP-3351548-B1 CROSSLINKED NUCLEIC ACID GUNA, METHOD FOR PRODUCING SAME, AND INTERMEDIATE COMPOUND MITSUBISHI TANABE PHARMA CORP (JP) 2025-08-20 EP disclosed
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-111689929-B Sulfur fluoride (VI) compound and preparation method thereof 斯克里普斯研究所 2024-05-31 CN disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed
CN-103781904-A Method for inhibiting protease in biological sample containing pancreatic juice component OLYMPUS CORP 2014-05-07 CN disclosed
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed
JP-H0334937-A PRODUCTION OF M-FLUORO AROMATIC COMPOUND IHARA CHEM IND CO LTD 1991-02-14 JP disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4156609-A FOR DIFFUSION TRANSFER PROCESSES, BALLASTS EASTMAN KODAK COMPANY (US) 1979-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 KMT2A 1800/4885GAA 2319/4885HTT 3856/4885
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD RIOX2, ORC3, DCLRE1A KMT2A 4014/4885GAA 4545/4885HTT 4632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.