SCHEMBL444998

SCHEMBL444998

CCO[Si](C)(CCCNCCC[Si](C)(OCC)OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 1/20 0.35
SAT1 P21673 1/20 0.32
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3301162 0.98 CYP2C19 (0.35) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL12002879 0.94 PAOX (0.39) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL554523 0.94 TSHR (0.42) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL30325785 0.94 ALDH1A1 (0.37) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL30325685 0.94 ALDH1A1 (0.37) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL37492 0.92 CA12 (0.42) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL1135938 0.91 CYP2C19 (0.44) CYP2C19TSHRMEN1GLAKMT2A
SCHEMBL25227614 0.90 CA12 (0.41) CYP2C19ALDH1A1TSHRMEN1GLA
SCHEMBL16829899 0.90 ALDH1A1 (0.50) CYP2C19ALDH1A1TSHRCYP1A2PAOX
SCHEMBL30998852 0.90 ALDH1A1 (0.50) CYP2C19ALDH1A1TSHRCYP1A2PAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 682 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637599-B2 Two-component polyurethane adhesive composition for film lamination in hot filling application HENKEL AG & CO. KGAA (DE) 2026-05-26 US claimed
US-12577447-B2 Two-component polyurethane adhesive composition for film lamination HENKEL AG & CO. KGAA (DE) 2026-03-17 US claimed
WO-2026041693-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-26 WO claimed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP claimed
US-20250325465-A1 COSMETIC COLORING COMPOSITIONS CONTAINING MOISTURE CURABLE SILICONE POLYETHYLENEIMINE RESIN HENKEL AG & CO KGAA (DE) 2025-10-23 US claimed
EP-4573146-A1 MOISTURE CURABLE SILICONE POLYETHYLENEIMINE RESIN Henkel AG & Co. KGaA (DE) 2025-06-25 EP claimed
EP-4370571-B1 POLYURETHANE ADHESIVE COMPOSITION FOR FILM LAMINATION HENKEL AG & CO KGAA (DE) 2025-05-14 EP claimed
EP-4370569-B1 TWO-COMPONENT POLYURETHANE ADHESIVE COMPOSITION CONTAINING METHOXYSILANE FUNCTIONALIZED ISOCYANATE COMPOUND FOR FILM LAMINATION HENKEL AG & CO KGAA (DE) 2025-05-14 EP claimed
EP-4370570-B1 TWO-COMPONENT POLYURETHANE ADHESIVE COMPOSITION FOR FILM LAMINATION IN HOT FILLING APPLICATION HENKEL AG & CO KGAA (DE) 2025-05-14 EP claimed
EP-4370568-B1 TWO-COMPONENT POLYURETHANE ADHESIVE COMPOSITION FOR FILM LAMINATION HENKEL AG & CO KGAA (DE) 2025-05-14 EP claimed
WO-2010086568-A1 COSMETIC COMPOSITION COMPRISING AN AQUEOUS DISPERSION OF POLYSILOXANE/POLYUREA AND A SILANE AND A METHOD FOR COSMETIC TREATMENT L'OREAL (FR) 2010-08-05 WO claimed
EP-1718689-B1 SILANE FORMULATION FOR MOISTURE-CROSSLINKING HYBRID ADHESIVES AND SEALANTS EVONIK DEGUSSA GMBH (DE) 2010-03-10 EP claimed
US-20080073815-A1 Vulcanizable composition based on ethylene-vinyl acetate copolymers, preparation thereof and use for production of products with elastomeric properties LANXESS DEUTSCHLAND GMBH (DE) 2008-03-27 US claimed
EP-1894947-A1 Vulcanisable compound based on ethylene-vinyl acetate copolymers, their manufacture and use in the manufacture of articles with rubber elastomer characteristics Lanxess Deutschland GmbH (DE) 2008-03-05 EP claimed
EP-1767187-A2 Cosmetic composition comprising an organic silicium compound and process for shaping hair L'OREAL (FR) 2007-03-28 EP claimed
EP-1718689-A2 SILANE FORMULATION FOR MOISTURE-CROSSLINKING HYBRID ADHESIVES AND SEALANTS Degussa GmbH (DE) 2006-11-08 EP claimed
WO-2005080462-A2 SILANE FORMULATION FOR MOISTURE-CROSSLINKING HYBRID ADHESIVES AND SEALANTS DEGUSSA AG (DE) 2005-09-01 WO claimed
WO-2005028603-A1 SILICATE DERIVED SOL-GELS SENSITIVE TO WATER CONTENT CHANGE GENENCOR INTERNATIONAL, INC. (US) 2005-03-31 WO claimed
WO-2005028604-A1 SILICA DERIVED SOL-GELS SENSITIVE TO WATER CONTENT CHANGE GENENCOR INTERNATIONAL, INC. (US) 2005-03-31 WO claimed
WO-2003035252-A1 CHEMICAL MODIFICATION OF PARTICLE SURFACES BY CROSS-LINKING MERCK PATENT GMBH (DE) 2003-05-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637599-B2 Two-component polyurethane adhesive composition for film lamination in hot filling application EPHX2, GJB2, GJA1 CYP2C19 1801/4885ALDH1A1 177/4885TSHR 4866/4885
US-12577447-B2 Two-component polyurethane adhesive composition for film lamination SMCHD1, DDT, ADH1C CYP2C19 3048/4885ALDH1A1 96/4885TSHR 4719/4885
US-20250325465-A1 COSMETIC COLORING COMPOSITIONS CONTAINING MOISTURE CURABLE SILICONE POLYETHYLENEIMINE RESIN ASH2L, RAD23B, H1-2 CYP2C19 1524/4885ALDH1A1 1013/4885TSHR 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.