Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460423 | 0.89 | LTB4R (0.37) | CYSLTR2CYSLTR1S1PR1S1PR3S1PR2 | |
| SCHEMBL4448976 | 0.82 | TSHR (0.42) | TSHRSCDPPARALTB4RLTB4R2 | |
| SCHEMBL4450311 | 0.81 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1S1PR1S1PR3S1PR2 | |
| SCHEMBL4450025 | 0.78 | TSHR (0.36) | TSHRPPARAPPARGCNR1CNR2 | |
| SCHEMBL4450027 | 0.73 | BRD4 (0.44) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL4453277 | 0.70 | LTB4R (0.47) | TSHRLTB4RLTB4R2CNR1CNR2 | |
| SCHEMBL13956434 | 0.70 | LTB4R (0.47) | TSHRLTB4RLTB4R2CNR1CNR2 | |
| SCHEMBL4460104 | 0.69 | BRD4 (0.34) | PPARAPPARG | |
| SCHEMBL4447372 | 0.69 | BRD4 (0.34) | PPARAPPARG | |
| SCHEMBL4445408 | 0.68 | TSHR (0.41) | TSHRSCDPPARALTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |