Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460104 | 0.86 | BRD4 (0.34) | BRD4HSD17B1PPARGPPARDPPARA | |
| SCHEMBL4460423 | 0.81 | LTB4R (0.37) | PPARA | |
| SCHEMBL4458627 | 0.79 | BACE1 (0.42) | PPARD | |
| SCHEMBL4447366 | 0.74 | BRD4 (0.36) | BRD4HSD17B1PPARGPPARDPPARA | |
| SCHEMBL7974213 | 0.74 | ALDH1A1 (0.44) | PPARGPPARDPPARA | |
| SCHEMBL2304117 | 0.69 | KDM4E (0.44) | HSD17B1 | |
| SCHEMBL4450029 | 0.69 | CYSLTR2 (0.36) | PPARGPPARA | |
| SCHEMBL4447367 | 0.68 | BRD4 (0.64) | BRD4 | |
| SCHEMBL2928705 | 0.66 | BRD4 (0.46) | BRD4 | |
| SCHEMBL2929677 | 0.65 | LTB4R (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482484-B2 | Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia | MERCK PATENT GMBH (DE) | 2009-01-27 | — | — | US | disclosed |