Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 10/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442751 | 0.84 | CNR1 (0.38) | CNR2CNR1ALDH1A1MAPK1HPGD | |
| SCHEMBL4452191 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL19753110 | 0.69 | CHRNA7 (0.39) | HTR2AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24089462 | 0.69 | ALOX5 (0.46) | ALDH1A1TSHRLMNAMAPK1KDM4E | |
| SCHEMBL10729086 | 0.68 | PDGFRB (0.38) | HTR2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4441212 | 0.67 | ACMSD (0.36) | ALDH1A1KMT2AKDM4EHPGDNPC1 | |
| SCHEMBL3365472 | 0.67 | CNR2 (0.42) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL22135589 | 0.66 | PDE10A (0.44) | LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10726933 | 0.66 | PDGFRB (0.38) | HTR2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL20624818 | 0.66 | PDE4A (0.34) | CNR2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476691-B2 | Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors | LABORATOIRE THERAMEX (MC) | 2009-01-13 | — | — | US | disclosed |