Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450293 | 0.81 | HTR2A (0.38) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL4441212 | 0.79 | ACMSD (0.36) | ALDH1A1KMT2AHPGDKDM4ENPC1 | |
| SCHEMBL10729086 | 0.73 | PDGFRB (0.38) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL10726933 | 0.72 | PDGFRB (0.38) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL8601229 | 0.70 | CA2 (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL4442739 | 0.70 | CA2 (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL4438841 | 0.70 | CA2 (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL4442733 | 0.70 | CA2 (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL4442755 | 0.70 | CA2 (0.47) | NPC1RAB9AMAPT | |
| SCHEMBL26045395 | 0.69 | ALDH1A1 (0.49) | ALDH1A1TSHRMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476691-B2 | Sulfamate benzothiophene derivatives as steroid sulfatase inhibitors | LABORATOIRE THERAMEX (MC) | 2009-01-13 | — | — | US | disclosed |