Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570597 | 0.78 | AR (0.55) | ARMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL8400694 | 0.77 | AR (0.50) | ARMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL29601087 | 0.77 | AR (0.50) | ARMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL28226542 | 0.76 | MAPT (0.40) | MAPTALDH1A1MAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5637278 | 0.74 | MAOB (0.42) | ARMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27557345 | 0.74 | MAOB (0.48) | MAPTALDH1A1MAPK1L3MBTL1MAOB | |
| SCHEMBL8519336 | 0.72 | PTGS2 (0.48) | ARMAPTTHRBALDH1A1HSD17B10 | |
| SCHEMBL2557627 | 0.71 | TSHR (0.50) | ARMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL8569987 | 0.71 | TSHR (0.50) | ARMAPTTHRBALDH1A1MAPK1 | |
| SCHEMBL2550694 | 0.71 | TSHR (0.50) | ARMAPTTHRBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992361-B1 | Remedy or preventive for digestive ulcer | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |