Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400694 | 1.00 | AR (0.50) | ARPTGS2MAPTTHRBCYP1A2 | |
| SCHEMBL8519336 | 0.95 | PTGS2 (0.48) | ARPTGS2MAPTTHRBCYP1A2 | |
| SCHEMBL2980868 | 0.93 | PTGS2 (0.49) | ARPTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5983793 | 0.93 | PTGS2 (0.49) | ARPTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6230783 | 0.89 | AR (0.47) | ARPTGS2MAPTCYP1A2CYP3A4 | |
| SCHEMBL27652067 | 0.85 | AR (0.44) | ARPTGS2MAPTTHRBTSHR | |
| SCHEMBL28024924 | 0.83 | AR (0.52) | ARPTGS2MAPTTHRBTSHR | |
| SCHEMBL4599675 | 0.81 | AR (0.50) | ARMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8672850 | 0.80 | PTGS2 (0.59) | PTGS2MAPTTLR8ALDH1A1L3MBTL1 | |
| SCHEMBL27613330 | 0.80 | MEN1 (0.42) | ARPTGS2MAPTTHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237407-A1 | PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLINE-3-ONE | THOR GmbH (DE) | 2023-09-06 | — | — | EP | disclosed |
| CN-116457337-A | Method for preparing 1, 2-benzisothiazolin-3-one | 托尔有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022089774-A1 | PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLINE-3-ONE | THOR GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |