Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601087 | 1.00 | AR (0.50) | ARPTGS2MAPTTHRBCYP1A2 | |
| SCHEMBL8519336 | 0.95 | PTGS2 (0.48) | ARPTGS2MAPTTHRBCYP1A2 | |
| SCHEMBL2980868 | 0.93 | PTGS2 (0.49) | ARPTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5983793 | 0.93 | PTGS2 (0.49) | ARPTGS2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6230783 | 0.89 | AR (0.47) | ARPTGS2MAPTCYP1A2CYP3A4 | |
| SCHEMBL27652067 | 0.85 | AR (0.44) | ARPTGS2MAPTTHRBTSHR | |
| SCHEMBL28024924 | 0.83 | AR (0.52) | ARPTGS2MAPTTHRBTSHR | |
| SCHEMBL4599675 | 0.81 | AR (0.50) | ARMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8672850 | 0.80 | PTGS2 (0.59) | PTGS2MAPTTLR8ALDH1A1L3MBTL1 | |
| SCHEMBL27613330 | 0.80 | MEN1 (0.42) | ARPTGS2MAPTTHRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630518-B2 | Process for preparing 1,2-benzisothiazoline-3-one | THOR GMBH (DE) | 2026-05-19 | — | — | US | disclosed |
| US-20240076276-A1 | Process for Preparing 1,2-Benzisothiazoline-3-One | THOR GMBH (DE) | 2024-03-07 | — | — | US | disclosed |
| EP-4237407-A1 | PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLINE-3-ONE | THOR GmbH (DE) | 2023-09-06 | — | — | EP | disclosed |
| CN-116457337-A | Method for preparing 1, 2-benzisothiazolin-3-one | 托尔有限公司 | 2023-07-18 | — | — | CN | disclosed |
| WO-2022089774-A1 | PROCESS FOR PREPARING 1,2-BENZISOTHIAZOLINE-3-ONE | THOR GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |
| CN-108218777-A | A kind of sulphur substituted phenyl pyrazole class XOR inhibitor and preparation and application | 华南理工大学 | 2018-06-29 | — | — | CN | disclosed |
| CN-1187346-C | Cyanothiophenyl balogen and preparation of 3-substituted benzoisothiazole therefrom | SUMITOMO SEIKA K K (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1289770-A | Cyanothiophenyl balogen and preparation of 3-substituted benzoisothiazole therefrom | SUMITOMO SEIKA K K (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1061975-C | Cyanothiophenyl halide and process for producing the same | SUMITOMO SEIKA CHEMICALS (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-0741129-B1 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5756806-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5679827-A | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| CN-1138032-A | Cyanothiophenyl halides and process for preparing 3-substituted benzisothiazoles using same | SUMITOMO SEIKA CHEMICALS (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0741129-A2 | Cyanobenzenesulfenyl halide and process for preparation of 3-substituted benzisothiazole using it | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630518-B2 | Process for preparing 1,2-benzisothiazoline-3-one | CBR1, SULT1A1, ARSA | AR 3135/4885PTGS2 2908/4885MAPT 4855/4885 |
| US-20240076276-A1 | Process for Preparing 1,2-Benzisothiazoline-3-One | ARSA, AOX1, SULT1A1 | AR 1930/4885PTGS2 3476/4885MAPT 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.