SCHEMBL4453348

SCHEMBL4453348

Clc1cc(Cl)c(Cl)c(-c2ccccc2Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP2A6 P11509 1/20 0.44
DPP4 P27487 1/20 0.42
PLA2G7 Q13093 1/20 0.41
PTPN1 P18031 1/20 0.41
PDK2 Q15119 1/20 0.40
TSHR P16473 2/20 0.39
AHR P35869 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
RAB9A P51151 1/20 0.39
PTPRC P08575 1/20 0.38
S100A4 P26447 1/20 0.38
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29765253 1.00 ALDH1A1 (0.48) ALDH1A1CYP2A6DPP4PLA2G7PTPN1
SCHEMBL4456505 0.86 ALDH1A1 (0.48) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL31339487 0.83 CYP2A6 (0.41) ALDH1A1CYP2A6DPP4PLA2G7PTPN1
SCHEMBL2930780 0.83 ALDH1A1 (0.69) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4454535 0.79 TP53 (0.52) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL4459798 0.79 AHR (0.50) ALDH1A1CYP2A6DPP4PLA2G7TSHR
SCHEMBL4456396 0.79 ALDH1A1 (0.50) ALDH1A1CYP2A6PDK2TSHRAHR
SCHEMBL4450035 0.79 AHR (0.61) ALDH1A1TSHRAHRHPGDHSD17B10
SCHEMBL29387186 0.78 CYP2A6 (0.50) ALDH1A1CYP2A6DPP4PLA2G7PDK2
SCHEMBL4450486 0.78 CYP2A6 (0.50) ALDH1A1CYP2A6DPP4PLA2G7PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed