SCHEMBL4456481

SCHEMBL4456481

Clc1cc(Cl)c(-c2cccc(Cl)c2Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
NOTUM Q6P988 2/20 0.41
IDO1 P14902 1/20 0.41
AHR P35869 2/20 0.41
TSHR P16473 1/20 0.41
PDK2 Q15119 1/20 0.41
P2RX7 Q99572 1/20 0.40
CYP2D6 P10635 1/20 0.39
MAOA P21397 1/20 0.39
MAPK1 P28482 1/20 0.39
ADRA1A P35348 1/20 0.39
SCN4A P35499 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
PDE3A Q14432 1/20 0.39
SCN5A Q14524 1/20 0.39
SCN9A Q15858 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4456270 0.87 TSHR (0.46) NOTUMIDO1TSHRPDK2P2RX7
SCHEMBL4456505 0.84 ALDH1A1 (0.48) ALDH1A1NOTUMIDO1AHRTSHR
SCHEMBL4450215 0.82 CYP3A4 (0.42) ALDH1A1NOTUMIDO1AHRTSHR
SCHEMBL4456396 0.81 ALDH1A1 (0.50) ALDH1A1AHRTSHRPDK2SCN2A
SCHEMBL4453481 0.81 NOTUM (0.41) ALDH1A1NOTUMIDO1AHRTSHR
SCHEMBL4450486 0.80 CYP2A6 (0.50) ALDH1A1IDO1AHRTSHRPDK2
SCHEMBL29387186 0.80 CYP2A6 (0.50) ALDH1A1IDO1AHRTSHRPDK2
SCHEMBL29624838 0.80 TSHR (0.44) ALDH1A1NOTUMIDO1TSHRPDK2
SCHEMBL2229304 0.80 TSHR (0.44) ALDH1A1NOTUMIDO1TSHRPDK2
SCHEMBL4456479 0.79 AHR (0.45) NOTUMIDO1AHRTSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed