SCHEMBL1720546

SCHEMBL1720546

Nc1ccc(-c2ccc(N)c(-c3ccc(-c4ccccc4)cc3)c2-c2ccc(-c3ccccc3)cc2)c(-c2ccc(-c3ccccc3)cc2)c1-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
TAAR1 Q96RJ0 2/20 0.48
CYP3A4 P08684 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 5/20 0.47
LMNA P02545 3/20 0.47
MAPT P10636 3/20 0.47
HTT P42858 3/20 0.47
KDM4E B2RXH2 2/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
HSP90AA1 P07900 1/20 0.47
ALOX15 P16050 1/20 0.47
ALOX12 P18054 1/20 0.47
MAOA P21397 3/20 0.41
FGR P09769 1/20 0.41
PIM1 P11309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297637 0.95 ALDH1A1 (0.48) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL30866155 0.88 HSD17B10 (0.52) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL845162 0.88 HSD17B10 (0.52) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL1727316 0.88 HSD17B10 (0.58) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL18241644 0.88 HSD17B10 (0.58) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL2069054 0.87 ALDH1A1 (0.52) HSD17B10CYP3A4TDP1ALDH1A1LMNA
Ammonia Solution, Strong SCHEMBL28028584 0.86 HSD17B10 (0.50) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL9550986 0.85 HSD17B10 (0.54) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL651427 0.85 HSD17B10 (0.54) HSD17B10TAAR1CYP3A4TDP1ALDH1A1
SCHEMBL29546125 0.85 HSD17B10 (0.50) HSD17B10TAAR1CYP3A4TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240107793-A1 SHEET RESISTANCE COMPONENT NOVALED GMBH (DE) 2024-03-28 US disclosed
US-11711934-B2 Metal amides for use as HIL for an organic light-emitting diode (OLED) NOVALED GMBH (DE) 2023-07-25 US disclosed
US-20230126203-A1 An Organic Electronic Device Comprising an Anode Layer, a Cathode Layer, at Least One Emission Layer (EML) and at Least One Hole Injection Layer (HIL) NOVALED GMBH (DE) 2023-04-27 US disclosed
US-20230131369-A1 An Organic Electronic Device Comprising a Hole Injection Layer That Comprises a Hole Transport Compound NOVALED GMBH (DE) 2023-04-27 US disclosed
US-20230097962-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-03-30 US disclosed
US-20220407029-A1 Metal Amides for Use as HIL for an Organic Light-Emitting Diode (OLED) NOVALED GMBH (DE) 2022-12-22 US disclosed
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-12-13 US disclosed
US-11394000-B2 Electron buffering materials, electron transport materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-07-19 US disclosed
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
US-11075352-B2 Metal amides for use as HIL for an organic light-emitting diode (OLED) NOVALED GMBH (DE) 2021-07-27 US disclosed
US-20150097162-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2015-04-09 US disclosed
US-20130221334-A1 THIADIAZOLE, COMPOUND FOR LIGHT-EMITTING ELEMENTS, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-08-29 US disclosed
US-20130037784-A1 THIADIAZOLE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20130037785-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2013-02-14 US disclosed
US-20120268003-A1 LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC DEVICE SEIKO EPSON CORPORATION (JP) 2012-10-25 US disclosed
US-20120262057-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2012-10-18 US disclosed
EP-1486549-B1 ORGANIC ELECTROLUMINESCENT ELEMENT TOYOTA JIDOSHOKKI KK (JP) 2012-01-11 EP disclosed
US-7338720-B2 Organic electroluminescent element KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2008-03-04 US disclosed
US-20050089713-A1 Organic electroluminescent element KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2005-04-28 US disclosed
EP-1486549-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2004-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11394000-B2 Electron buffering materials, electron transport materials and organic electroluminescent device comprising the same SLC9A2, SLC8B1, SLC8A1 HSD17B10 1937/4885TAAR1 3456/4885CYP3A4 3190/4885
US-20120262057-A1 THIADIAZOLE-BASED COMPOUND, LIGHT EMITTING ELEMENT COMPOUND, LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AUTHENTICATION DEVICE, AND ELECTRONIC APPARATUS RIF1, HRH1, HRH3 HSD17B10 1045/4885TAAR1 567/4885CYP3A4 47/4885
US-20230097962-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices AOX1, CYP1B1, CYP1A1 HSD17B10 991/4885TAAR1 319/4885CYP3A4 45/4885
US-11527728-B2 Organic electroluminescent compounds and organic electroluminescent device comprising the same VDAC1, VDAC2, VAPA HSD17B10 3784/4885TAAR1 3557/4885CYP3A4 3298/4885
US-20130037784-A1 THIADIAZOLE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING APPARATUS, AUTHENTICATION APPARATUS, AND ELECTRONIC DEVICE CYP3A4, CYP2E1, TH HSD17B10 1574/4885TAAR1 1591/4885CYP3A4 1/4885
US-20050089713-A1 Organic electroluminescent element SOD3, CELF2, SOD1 HSD17B10 1850/4885TAAR1 4114/4885CYP3A4 680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.