Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286875 | 0.83 | MAPK1 (0.35) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL7737438 | 0.80 | MAPK1 (0.41) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL7737435 | 0.80 | MAPK1 (0.41) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL737574 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL1061705 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL24243949 | 0.77 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL8611387 | 0.77 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL3284526 | 0.75 | ALDH1A1 (0.43) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL20590360 | 0.75 | ALDH1A1 (0.43) | MAPK1ALDH1A1ALOX15CYP3A4MAPT | |
| SCHEMBL14255700 | 0.75 | ESR1 (0.54) | ALDH1A1ALOX15ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716409-B2 | Carboxylate terminated polymers and their use in impact-modified plastics | FIRESTONE POLYMERS, LLC (US) | 2014-05-06 | — | — | US | claimed |
| US-20080161448-A1 | Carboxylate Terminated Polymers and Their Use in Impact-Modified Plastics | FIRESTONE POLYMERS, LLC | 2008-07-03 | — | — | US | claimed |
| EP-1373323-B1 | CO2-TERMINATED RUBBER | FIRESTONE POLYMERS LLC (US) | 2007-02-28 | — | — | EP | claimed |
| US-7105613-B2 | CO2 terminated rubber for plastics | FIRESTONE POLYMERS, LLC (US) | 2006-09-12 | — | — | US | claimed |
| US-20050131153-A1 | CO2 terminated rubber for plastics | LION ELASTOMERS ORANGE, LLC | 2005-06-16 | — | — | US | claimed |
| US-6881795-B2 | CO2 terminated rubber for plastics | FIRESTONE POLYMERS, LLC (US) | 2005-04-19 | — | — | US | claimed |
| EP-1373323-A1 | CO2-TERMINATED RUBBER | Firestone Polymers, LLC (US) | 2004-01-02 | — | — | EP | claimed |
| US-20020183468-A1 | CO2 terminated rubber for plastics | LION ELASTOMERS ORANGE, LLC | 2002-12-05 | — | — | US | claimed |
| WO-2002079267-A1 | CO2-TERMINATED RUBBER | FIRESTONE POLYMERS, LLC (US) | 2002-10-10 | — | — | WO | claimed |
| CN-106232636-B | Ceramics forming with or conductive paste binder and their purposes | 株式会社可乐丽 | 2018-12-21 | — | — | CN | disclosed |
| EP-2111420-B1 | CARBOXYLATE TERMINATED POLYMERS AND THEIR USE IN IMPACT-MODIFIED PLASTICS | BRIDGESTONE CORP (JP) | 2017-05-31 | — | — | EP | disclosed |
| CN-106232636-A | Ceramics forming with or the binding agent of conductive paste and their purposes | 株式会社可乐丽 | 2016-12-14 | — | — | CN | disclosed |
| CN-101657475-B | Carboxylate terminated polymer and the purposes in impact-modified plastics thereof | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| US-8716409-B2 | Carboxylate terminated polymers and their use in impact-modified plastics | FIRESTONE POLYMERS, LLC (US) | 2014-05-06 | — | — | US | disclosed |
| US-4174431-A | CATALYST COMPRISING DIHYDROCARBYL MAGNESIUM AND ORGANIC ALKALI METAL COMPOUND | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4148984-A | TRIALKYLALUMINUM WITH ALKALI METAL COMPOUNDS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4139490-A | HIGH MOLECULAR WEIGHT POLYBUTADIENE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4107081-A | TRIHYDROCARBYLALUMINUM COMPOUNDS WITH ALKALI METAL COMPOUNDS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4076530-A | Dry photographic copying method for producing Te images | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
| US-3953542-A | CATALYST OF VANADIUM OR TITANIUM HALIDE, ALUMINUM TRIHYDROCARBON, AND A CARBONYL COMPOUND | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161448-A1 | Carboxylate Terminated Polymers and Their Use in Impact-Modified Plastics | ZYX, LPO, ALOX5 | MAPK1 2353/4885ALDH1A1 1176/4885TAAR1 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.