Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28819316 | 0.95 | MAPK1 (0.41) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL1061705 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL9858671 | 0.79 | TSHR (0.48) | MAPK1ALDH1A1ALOX15MAPTKMT2A | |
| SCHEMBL4450792 | 0.79 | MAPK1 (0.44) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL24243949 | 0.77 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL5682958 | 0.77 | — | — | |
| SCHEMBL10382218 | 0.77 | MAPK1 (0.42) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL9858415 | 0.77 | TSHR (0.52) | ALDH1A1MAPTTSHR | |
| SCHEMBL22361948 | 0.76 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL23747059 | 0.75 | KIF11 (0.41) | MAPK1ALDH1A1MAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135393-A1 | SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-05-15 | — | — | US | claimed |
| WO-2012140574-A1 | SUBSTITUTED CATECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-10-18 | — | — | WO | claimed |
| EP-0714425-B1 | PROCESS FOR MAKING COMPOSITIONS FOR PURIFYING SEMICONDUCTOR PROCESS GASES TO REMOVE LEWIS ACID AND OXIDANT IMPURITIES THEREFROM | MILLIPORE INVEST HOLDINGS LTD (US) | 2001-05-30 | — | — | EP | claimed |
| US-5531971-A | Process for purifying semiconductor process gases to remove lewis acid and oxidant impurities therefrom | MILLIPORE INVESTMENT HOLDINGS LIMITED (US) | 1996-07-02 | — | — | US | claimed |
| EP-0714425-A1 | PROCESS AND COMPOSITION FOR PURIFYING SEMICONDUCTOR PROCESS GASES TO REMOVE LEWIS ACID AND OXIDANT IMPURITIES THEREFROM | MILLIPORE INVESTMENT HOLDINGS LIMITED (US) | 1996-06-05 | — | — | EP | claimed |
| EP-0283961-B1 | Process and composition for purifying arsine, phosphine, ammonia and inert gases to remove Lewis acid and oxidant impurities therefrom | MILLIPORE INVEST HOLDINGS (US) | 1995-12-20 | — | — | EP | claimed |
| US-5385689-A | Inert support containing active scavenging species formed by depositing sodium, potassium, rubidium and/or cesium or their alloys and pyrolyzing | NOVAPURE CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| WO-1995001409-A1 | PROCESS AND COMPOSITION FOR PURIFYING SEMICONDUCTOR PROCESS GASES TO REMOVE LEWIS ACID AND OXIDANT IMPURITIES THEREFROM | MILLIPORE INVESTMENT HOLDINGS LIMITED (US) | 1995-01-12 | — | — | WO | claimed |
| EP-0291849-B1 | 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS | BASF Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | claimed |
| US-4797227-A | Process and composition for purifying hydrogen selenide and hydrogen telluride, to remove moisture and oxidant impurities therefrom | ADVANCED TECHNOLOGY MATERIALS INC. (US) | 1989-01-10 | — | — | US | claimed |
| EP-0291849-A2 | 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals | BASF Aktiengesellschaft (DE) | 1988-11-23 | — | — | EP | claimed |
| US-4781900-A | ANIONS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 1988-11-01 | — | — | US | claimed |
| EP-0283961-A2 | Process and composition for purifying arsine, phosphine, ammonia and inert gases to remove Lewis acid and oxidant impurities therefrom | MILLIPORE INVESTMENT HOLDINGS LIMITED (US) | 1988-09-28 | — | — | EP | claimed |
| US-4761395-A | SCAVENGERS | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 1988-08-02 | — | — | US | claimed |
| US-4611039-A | Wettable, gas permeable contact lens | PRECISION-COSMET CO., INC. (US) | 1986-09-09 | — | — | US | claimed |
| CN-111334002-B | Earplug manufacturing material and preparation method thereof | 湖南翰坤实业有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-103906768-A | Emulsion polymerization method using reactive emulsifying agent, aqueous polymer dispersion obtained by same, and polymer film | DAI ICHI KOGYO SEIYAKU CO LTD | 2014-07-02 | — | — | CN | disclosed |
| US-4603148-A | Macroreticulate polymer scavengers for the removal of impurities from inert fluids | HERCULES INCORPORATED (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0179969-A2 | Use of scavengers for the removal of impurities from inert fluids | HERCULES INCORPORATED (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4062883-A | Polymer-bound metallocarborane catalyst product and process | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135393-A1 | SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA | IL5, IL4, IL33 | MAPK1 715/4885ALDH1A1 1102/4885TAAR1 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.