Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036793 | 0.82 | NAALAD2 (0.37) | ALDH1A1NAALAD2HTR1DANPEPENPEP | |
| SCHEMBL19464263 | 0.82 | TBXAS1 (0.55) | CYP2C19 | |
| SCHEMBL12890269 | 0.82 | MAPT (0.48) | ALDH1A1RIPK1LMNAMAPTKDM4E | |
| SCHEMBL4943739 | 0.81 | NAALAD2 (0.46) | ALDH1A1NAALAD2TSHRCYP1A2CYP2D6 | |
| SCHEMBL167045 | 0.81 | ALDH1A1 (0.59) | ALDH1A1CYP2C19HTR1DLMNAMAPT | |
| SCHEMBL2300538 | 0.81 | ALDH1A1 (0.59) | ALDH1A1CYP2C19HTR1DLMNAMAPT | |
| SCHEMBL1144429 | 0.81 | ALDH1A1 (0.59) | ALDH1A1CYP2C19HTR1DLMNAMAPT | |
| SCHEMBL27321292 | 0.80 | ATM (0.46) | ALDH1A1NAALAD2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2267568 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8722488 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP2D6CYP2C19RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360707-A | Thrombopoietin activity modulating compounds and methods | LIGAND PHARM INC (US) | 2009-02-04 | — | — | CN | claimed |
| WO-2009154804-A2 | TWIN FLUOROPHORE PEPTIDE NUCLEIC ACID HYBRIDIZATION PROBES | THOMAS JEFFERSON UNIVERSITY (US) | 2009-12-23 | — | — | WO | disclosed |
| CN-101360707-A | Thrombopoietin activity modulating compounds and methods | LIGAND PHARM INC (US) | 2009-02-04 | — | — | CN | disclosed |
| US-6921822-B2 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-07-26 | — | — | US | disclosed |
| US-20040030181-A1 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030181-A1 | Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives | HPD, GRHPR, CYP4B1 | ALDH1A1 133/4885NAALAD2 1318/4885TSHR 3656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.