Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025846 | 0.63 | CHRNB2 (0.37) | CHRNB2CHRNA4PTGS1 | |
| SCHEMBL634391 | 0.63 | FASN (0.31) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL12150575 | 0.59 | KDM4E (0.43) | MEN1CYP3A4KMT2A | |
| SCHEMBL29897797 | 0.58 | — | — | |
| SCHEMBL11949184 | 0.58 | — | — | |
| SCHEMBL8404353 | 0.57 | CHRNB2 (0.55) | CHRNB2CHRNA4MEN1CYP3A4PTGS1 | |
| SCHEMBL9782940 | 0.55 | KMT2A (0.38) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL11382828 | 0.55 | MAPT (0.50) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL8051337 | 0.55 | SMN1; SMN2 (0.70) | MEN1KMT2A | |
| SCHEMBL2051779 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | claimed |
| EP-3523414-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | Henkel AG & Co. KGaA (DE) | 2019-08-14 | — | — | EP | claimed |
| WO-2018095814-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2018-05-31 | — | — | WO | claimed |
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | HENKEL AG & CO. KGAA (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | HENKEL AG & CO. KGAA (DE) | 2019-09-12 | — | — | US | disclosed |
| EP-3523414-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | Henkel AG & Co. KGaA (DE) | 2019-08-14 | — | — | EP | disclosed |
| WO-2018095814-A1 | CYCLIC KETALS AS FRAGRANCE PRECURSOR COMPOUNDS | HENKEL AG & CO. KGAA (DE) | 2018-05-31 | — | — | WO | disclosed |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | HENKEL AG & CO. KGAA (DE) | 2017-12-07 | — | — | US | disclosed |
| EP-3233781-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | Henkel AG & Co. KGaA (DE) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096539-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | HENKEL AG & CO. KGAA (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | YKI, Ytemiska Institutet AB (SE) | 2012-03-15 | — | — | US | disclosed |
| US-6437150-B1 | WHEN ACTIVATED, THE ESTERS, CARBONATES, OR CARBAMATES ARE CLEAVED TO FORM ONE OR MORE LACTONES AND ORGANOLEPTICS SUCH AS FRAGRANCES, OR MASKING AGENTS, OR ANTIMICROBIAL AGENTS; STABLE UNDER TRANSPORT AND STORAGE CONDITIONS | GIVAUDAN SA (CH) | 2002-08-20 | — | — | US | disclosed |
| US-6348618-B1 | PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-02-19 | — | — | US | disclosed |
| US-6258854-B1 | KETONE ETHERS FOR ODORS | GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) | 2001-07-10 | — | — | US | disclosed |
| US-6222062-B1 | USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-1090624-A2 | Beta ketoester | Givaudan SA (CH) | 2001-04-11 | — | — | EP | disclosed |
| EP-0983990-A2 | Ketones useful as precursors for organoleptic compounds | Givaudan Roure (International) S.A. (CH) | 2000-03-08 | — | — | EP | disclosed |
| EP-0953562-A1 | Beta, gamma-unsaturated delta-keto esters | Givaudan Roure (International) S.A. (CH) | 1999-11-03 | — | — | EP | disclosed |
| EP-0952142-A1 | Compounds with protected hydroxy groups | Givaudan Roure (International) S.A. (CH) | 1999-10-27 | — | — | EP | disclosed |
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065179-A1 | PRODRUG COMPRISING BETA-KETO CARBOXYLIC ACID, BETA-KETO CARBOXYLIC ACID SALT OR BETA-KETO CARBOXYLIC ACID ESTER FOR DRUG DELIVERY | BCKDK, KHK, CA7 | CHRNB2 1435/4885CHRNA4 1728/4885MEN1 2158/4885 |
| US-10941156-B2 | Cyclic ketals as fragrance precursor compounds | KCNK5, KLK5, KCNA1 | CHRNB2 3459/4885CHRNA4 2286/4885MEN1 395/4885 |
| US-20190276469-A1 | Cyclic Ketals As Fragrance Precursor Compounds | KCNK5, KLK5, KCNA1 | CHRNB2 3459/4885CHRNA4 2286/4885MEN1 395/4885 |
| US-20170349858-A1 | PHOTOLABILE FRAGRANCE PRECURSOR COMPOUND | TRPA1, CYP1A1, TRPV1 | CHRNB2 3012/4885CHRNA4 2614/4885MEN1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.