Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MTTP | P55157 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MMP14 | P50281 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450969 | 1.00 | TACR3 (0.52) | TACR3LMNAMEN1MAPK1KMT2A | |
| SCHEMBL4448206 | 0.87 | MTTP (0.52) | TACR3LMNAMEN1MAPK1KMT2A | |
| SCHEMBL4448204 | 0.87 | MTTP (0.52) | TACR3LMNAMEN1MAPK1KMT2A | |
| SCHEMBL4446676 | 0.85 | LMNA (0.49) | TACR3LMNAMEN1MAPK1KMT2A | |
| SCHEMBL4446680 | 0.85 | LMNA (0.49) | TACR3LMNAMEN1MAPK1KMT2A | |
| SCHEMBL4444765 | 0.80 | S1PR3 (0.56) | TACR3LMNAMMP1MMP3MMP2 | |
| SCHEMBL4447516 | 0.79 | TNFRSF1A (0.47) | TACR3LMNAMEN1KMT2AMTTP | |
| SCHEMBL4447518 | 0.79 | TNFRSF1A (0.47) | TACR3LMNAMEN1KMT2AMTTP | |
| SCHEMBL4450275 | 0.79 | TNFRSF1A (0.47) | TACR3LMNAMEN1KMT2AMTTP | |
| SCHEMBL4443046 | 0.79 | ALDH1A1 (0.51) | TACR3LMNAMMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | NEUROMED PHRAMACEUTICALS LTD. (CA) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012010-A1 | Amino acid derivatives as calcium channel blockers | CACNA1G, CACNA1H, CACNA1I | TACR3 556/4885LMNA 1070/4885MEN1 1973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.