Xanthene

Xanthene

SCHEMBL4451064

c1ccc2c(c1)-c1ccccc1-2.c1ccc2c(c1)Cc1ccccc1O2

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.85
MAOB P27338 3/20 0.85
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NPC1 O15118 2/20 0.41
LMNA P02545 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
SETD7 Q8WTS6 1/20 0.41
MAPKAPK2 P49137 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ACSL1 P33121 1/20 0.39
BCHE P06276 1/20 0.38
CES1 P23141 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Xanthene SCHEMBL6650489 0.93 MAOA (0.81) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL29378346 0.92 MAOA (1.00) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL9339684 0.92 MAOA (1.00) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL30586075 0.92 MAOA (1.00) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL4267 0.92 MAOA (1.00) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL23355281 0.90 MAOA (0.94) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL1673119 0.90 MAOA (0.94) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL11222980 0.90 MAOA (0.94) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL11600668 0.90 MAOA (0.94) MAOAMAOBGAANPSR1NPC1
Xanthene SCHEMBL11214757 0.90 MAOA (0.94) MAOAMAOBGAANPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101511899-A Straight-chain compound containing (methyl) acryloyl, star-shaped compound containing (methyl) acryloyl and method for manufacturing them DPC K K (JP) 2009-08-19 CN disclosed
US-7514507-B2 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-04-07 US disclosed
US-20070142611-A1 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-21 US disclosed