Xanthene

Xanthene

SCHEMBL6650489

c1ccc2c(c1)Cc1ccccc1-2.c1ccc2c(c1)Cc1ccccc1O2

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.81
MAOB P27338 2/20 0.81
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
GAA P10253 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
BCHE P06276 1/20 0.41
CES1 P23141 1/20 0.41
SRD5A2 P31213 1/20 0.41
SETD7 Q8WTS6 1/20 0.40
MAPKAPK2 P49137 1/20 0.40
MAPK8 P45983 2/20 0.39
MAPK9 P45984 2/20 0.39
PLK4 O00444 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL28942808 0.93 MAOA (0.68) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL4451064 0.93 MAOA (0.85) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL29378346 0.90 MAOA (1.00) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL30586075 0.90 MAOA (1.00) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL9339684 0.90 MAOA (1.00) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL4267 0.90 MAOA (1.00) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL23355281 0.87 MAOA (0.94) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL6192065 0.87 MAOA (0.94) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL1673119 0.87 MAOA (0.94) MAOAMAOBNPC1LMNARAB9A
Xanthene SCHEMBL11222980 0.87 MAOA (0.94) MAOAMAOBNPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110416419-A Organic electroluminescence device JIANGSU SUNERA TECH CO LTD 2019-11-05 CN claimed
CN-110343085-A It is a kind of using spiral shell xanthene fluorenes as the compound of core, preparation method and applications 江苏三月光电科技有限公司 2019-10-18 CN claimed
CN-109748909-A The compound of a kind of fluorenes of xanthene containing spiral shell and nitrogenous hexa-member heterocycle, preparation method and its application in organic electroluminescence device 江苏三月光电科技有限公司 2019-05-14 CN claimed
CN-109574996-A It is a kind of using spiral shell xanthene fluorenes as the compound of core and its application on organic electroluminescence device 江苏三月光电科技有限公司 2019-04-05 CN claimed
CN-107973770-A A kind of preparation method of the loop coil class delayed fluorescence material of cyano group substitution 南京邮电大学 2018-05-01 CN claimed
CN-103304558-B Containing benzoyloxy spiral shell fluorenes oxa-anthryl benzoxazine and preparation method HARBIN ENGINEERING UNIV. (CN) 2016-01-27 CN claimed
CN-104710399-A Novel blue light-emitting material and preparation thereof FANGYUAN GLOBAL YANCHENG PHOTOELECTRIC TECHNOLOGY CO LTD 2015-06-17 CN claimed
CN-102229623-B Spirofluorene xanthene phosphine oxide electro-phosphorescent main materials and synthesis and application methods thereof UNIV NANJING POSTS & TELECOMM 2013-12-25 CN claimed
CN-103304558-A Spirofluorene xanthene benzoxazine containing benzoyloxy group and preparation method thereof UNIV HARBIN ENG 2013-09-18 CN claimed
CN-101870865-B Spray ring replacing pyrene blue-light semiconductor material and non-doping electric blue-light device thereof UNIV NANJING POSTS & TELECOMM 2013-05-08 CN claimed
CN-102977006-A Pyridine-fluorene organic electrophosphorescence main body luminescent material and preparation method thereof UNIV NANJING POSTS & TELECOMM 2013-03-20 CN claimed
CN-102786508-A Spiro-fluorene-9,9-xanthene bipolar luminescent material, its preparation method and its application method UNIV NANJING POSTS & TELECOMM 2012-11-21 CN claimed
CN-102229623-A Spirofluorene xanthene phosphine oxide electro-phosphorescent main materials and synthesis and application methods thereof UNIV NANJING POSTS & TELECOMM 2011-11-02 CN claimed
CN-102127420-A Spiro-iridium organic electrophosphorescent material and preparation method thereof UNIV NANJING POSTS & TELECOMM 2011-07-20 CN claimed
CN-102050782-A Preparation method of spirofluorene acridine intermediate Nanjing fangyuan global display technology co ltd 2011-05-11 CN claimed
CN-101870865-A Spray ring replacing pyrene blue-light semiconductor material and non-doping electric blue-light device thereof UNIV NANJING POSTS & TELECOMM 2010-10-27 CN claimed
CN-101643381-A Diarylfluorene intermediate preparation method UNIV NANJING POSTS & TELECOMM 2010-02-10 CN claimed
CN-101440082-A Spirofluorene xanthene material, and preparation and use thereof UNIV NANJING POSTS & TELECOMM (CN) 2009-05-27 CN claimed
US-11917909-B2 Organic compound and organic electroluminescence device using the same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2024-02-27 US disclosed
EP-0904262-B1 CONFORMATIONALLY RESTRICTED AROMATIC INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD BRISTOL MYERS SQUIBB CO (US) 2004-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917909-B2 Organic compound and organic electroluminescence device using the same SLC25A21, PIEZO1, SLCO4C1 MAOA 561/4885MAOB 1270/4885NPC1 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.