SCHEMBL453395

SCHEMBL453395

NC(O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.52
F2 P00734 1/20 0.52
LMNA P02545 3/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2C P18825 1/20 0.52
HIF1A Q16665 1/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.44
AOC3 Q16853 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451068 1.00 DPP4 (0.52) DPP4F2LMNAADRA2AADRA2C
SCHEMBL29001563 1.00 DPP4 (0.52) DPP4F2LMNAADRA2AADRA2C
SCHEMBL29001566 0.87 EPHX1 (0.43) DPP4F2LMNAADRA2AADRA2C
SCHEMBL29001569 0.87 LMNA (0.49) DPP4F2LMNAADRA2AADRA2C
SCHEMBL29001567 0.87 IDO1 (0.52) DPP4LMNAADRA2AADRA2CHIF1A
SCHEMBL7047936 0.78 KDM4E (0.65) DPP4F2LMNAADRA2AADRA2C
SCHEMBL19329295 0.78 DPP4 (0.68) DPP4F2LMNAADRA2AADRA2C
SCHEMBL6745618 0.77 DPP4 (0.58) DPP4F2LMNAADRA2AADRA2C
SCHEMBL13208856 0.77
SCHEMBL4348933 0.77 LMNA (0.48) DPP4F2LMNAADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114836486-B Method for synthesizing chiral beta-amino alcohol by enzyme catalysis 湖北大学 2023-05-12 CN claimed
CN-114836486-A Method for synthesizing chiral beta-amino alcohol by enzyme catalysis 湖北大学 2022-08-02 CN claimed
JP-3097780-A None JP disclosed
US-20250381762-A1 VERMICULITE LAMINATED FILM FOR VACUUM INSULATION PANEL, VACUUM INSULATION PANEL HAVING THE SAME AND REFRIGERATOR SAMSUNG ELECTRONICS CO LTD (KR) 2025-12-18 US disclosed
CN-114836486-B Method for synthesizing chiral beta-amino alcohol by enzyme catalysis 湖北大学 2023-05-12 CN disclosed
CN-114836486-A Method for synthesizing chiral beta-amino alcohol by enzyme catalysis 湖北大学 2022-08-02 CN disclosed
US-8871317-B2 Curable adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2014-10-28 US disclosed
EP-2613933-A2 CURABLE ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH Teknor Apex Company (US) 2013-07-17 EP disclosed
US-20120064274-A1 Curable adhesive system, method of assembly of distinct components therewith TEKNOR APEX COMPANY (US) 2012-03-15 US disclosed
WO-2012033519-A2 CURABLE ADHESIVE SYSTEM, METHOD OF ASSEMBLY OF DISTINCT COMPONENTS THEREWITH TEKNOR APEX COMPANY (US) 2012-03-15 WO disclosed
US-20100063320-A1 METHOD FOR PRODUCING FORMIC ACID BASF SE (DE) 2010-03-11 US disclosed
EP-2139837-A1 METHOD FOR PRODUCING FORMIC ACID BASF SE (DE) 2010-01-06 EP disclosed
WO-2008116799-A1 METHOD FOR PRODUCING FORMIC ACID BASF SE (DE) 2008-10-02 WO disclosed
EP-0386603-A3 BISPHENETHANOLAMINE F. HOFFMANN-LA ROCHE AG (CH) 1991-04-24 EP disclosed
JP-H0397780-A BONDING COMPOSITION TOYODA GOSEI CO LTD 1991-04-23 JP disclosed
EP-0386603-A2 Bisphenethanolamine F. HOFFMANN-LA ROCHE AG (CH) 1990-09-12 EP disclosed
US-3983289-A EPOXIDIZED ALKADIENE ALCOHOL ESTER OF POLYCARBOXYLIC ACID, B-STAGE RESIN MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063320-A1 METHOD FOR PRODUCING FORMIC ACID FAAH, HRH3, F2 DPP4 4303/4885F2 3/4885LMNA 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.