SCHEMBL4451198

SCHEMBL4451198

O=C1N=NOC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.47
SLC6A3 Q01959 1/20 0.47
ALDH1A1 P00352 5/20 0.41
CA2 P00918 1/20 0.41
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
POLB P06746 2/20 0.38
KMT2A Q03164 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.35
MAPK1 P28482 2/20 0.35
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR2B P41595 1/20 0.34
EPHX1 P07099 2/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31319113 0.71
SCHEMBL11428038 0.69 AKT1 (0.39) ALDH1A1KDM4EMAPTPOLBKMT2A
SCHEMBL31319128 0.69
Silver SCHEMBL31319093 0.69
SCHEMBL31319073 0.69
Silver SCHEMBL31319094 0.69
SCHEMBL11404807 0.68
SCHEMBL11407340 0.68 DAO (0.39) RAB9ASLC6A3CA2KDM4EMAPT
SCHEMBL31650964 0.67 ALDH1A1 (0.56) RAB9ASLC6A3ALDH1A1CA2KDM4E
SCHEMBL3117048 0.67 RAB9A (0.52) RAB9ASLC6A3ALDH1A1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023194626-A1 HERBICIDE COMPOSITION FOR THE CONTROL OF UNWANTED VEGETATION BELCHIM CROP PROTECTION NV (BE) 2023-10-12 WO claimed
JP-60115502-A None JP disclosed
US-12495798-B2 Nicotinamide compound and herbicidal composition comprising compound KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-12-16 US disclosed
WO-2023233303-A1 A PROCESS FOR PREPARING A LIQUID FORMULATION UPL LIMITED (IN) 2023-12-07 WO disclosed
WO-2023194626-A1 HERBICIDE COMPOSITION FOR THE CONTROL OF UNWANTED VEGETATION BELCHIM CROP PROTECTION NV (BE) 2023-10-12 WO disclosed
WO-2023194957-A1 A PROCESS FOR PREPARATION OF 3-[5-(DIFLUOROMETHOXY)-1- METHYL-3-(TRIFLUOROMETHYL)PYRAZOL-4- YLMETHYLSULFONYL]-4,5-DIHYDRO-5,5-DIMETHYL-1,2-OXAZOLE AND ITS INTERMEDIATES UPL LIMITED (IN) 2023-10-12 WO disclosed
WO-2023187829-A1 AN AGROCHEMICAL COMPOSITION UPL LIMITED (IN) 2023-10-05 WO disclosed
US-20220386607-A1 NICOTINAMIDE COMPOUND AND HERBICIDAL COMPOSITION COMPRISING COMPOUND Farmhannong Co., Ltd. (KR) 2022-12-08 US disclosed
EP-4050007-A1 NICOTINAMIDE COMPOUND AND HERBICIDAL COMPOSITION COMPRISING COMPOUND Korea Research Institute of Chemical Technology (KR) 2022-08-31 EP disclosed
CN-110818596-A Semicarbazide compound and preparation and application thereof 合肥锦绣田园化工科技有限公司 2020-02-21 CN disclosed
EP-0641316-B1 INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES UNIROYAL CHEM CO INC (US) 1997-01-22 EP disclosed
US-5567723-A Miticidal hydrazine compounds and their intermediates UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-10-22 US disclosed
US-5543404-A MITICIDES UNIROYAL CHEMICAL COMPANY, INC (US) 1996-08-06 US disclosed
US-5536746-A Insecticidal phenylhydrazine derivatives UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-07-16 US disclosed
US-5438123-A Miticides, nematocides UNIROYAL CHEMICAL COMPANY, INC. (US) 1995-08-01 US disclosed
EP-0641316-A1 INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES. UNIROYAL CHEM CO INC (US) 1995-03-08 EP disclosed
US-5367093-A Pesticides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-11-22 US disclosed
WO-1993010083-A1 INSECTICIDAL PHENYLHYDRAZINE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-05-27 WO disclosed
US-4725302-A Substituted phenylhydrazines and phenyloxadiazolinones and pesticidal usage thereof CIBA-GEIGY CORPORATION (US) 1988-02-16 US disclosed
JP-S60115502-A INSECTICIDE MITSUBISHI CHEM IND LTD 1985-06-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12495798-B2 Nicotinamide compound and herbicidal composition comprising compound NAMPT, SIRT1, SIRT6 RAB9A 2163/4885SLC6A3 1523/4885ALDH1A1 1218/4885
US-20220386607-A1 NICOTINAMIDE COMPOUND AND HERBICIDAL COMPOSITION COMPRISING COMPOUND NAMPT, SIRT1, SIRT6 RAB9A 2163/4885SLC6A3 1523/4885ALDH1A1 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.