Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451601 | 1.00 | CASP3 (0.43) | CASP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13783979 | 1.00 | CASP3 (0.43) | CASP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13784016 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL4462419 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL4462424 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL4460262 | 0.81 | ALDH1A1 (0.44) | CASP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4460265 | 0.81 | ALDH1A1 (0.44) | CASP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13783924 | 0.81 | ALDH1A1 (0.44) | CASP3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4330504 | 0.79 | MTOR (0.48) | MTOR | |
| SCHEMBL13783957 | 0.78 | RAB9A (0.54) | HPGDSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |