Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.45 |
| ▸ | RELA | Q04206 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451648 | 1.00 | TSHR (0.49) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL4469973 | 0.81 | TSHR (0.44) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL11096876 | 0.78 | TSHR (0.56) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL4462184 | 0.75 | ALDH1A1 (0.47) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL4462177 | 0.75 | ALDH1A1 (0.47) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL12890455 | 0.72 | TSHR (0.54) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL4455204 | 0.71 | RAB9A (0.43) | RAB9ASMN1; SMN2KMT2AGAANPC1 | |
| SCHEMBL4455208 | 0.71 | RAB9A (0.43) | RAB9ASMN1; SMN2KMT2AGAANPC1 | |
| SCHEMBL11220484 | 0.70 | TSHR (0.65) | TSHRRAB9ASMN1; SMN2KMT2AGAA | |
| SCHEMBL13278295 | 0.69 | TSHR (0.64) | TSHRRAB9ASMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |