Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455204 | 1.00 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL4459460 | 0.80 | ALOX5 (0.56) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL4459465 | 0.80 | ALOX5 (0.56) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL13408956 | 0.79 | ALDH1A1 (0.58) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL4452867 | 0.79 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL4452865 | 0.79 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL4466264 | 0.73 | KIF11 (0.45) | RAB9ANPC1PKMALDH1A1GAA | |
| SCHEMBL4451653 | 0.71 | TSHR (0.49) | RAB9ANPC1SMN1; SMN2MAPTPKM | |
| SCHEMBL5827952 | 0.71 | CSNK1D (0.56) | RAB9ANPC1SMN1; SMN2MAPTNFKB1 | |
| SCHEMBL13408929 | 0.71 | CSNK1D (0.56) | RAB9ANPC1SMN1; SMN2MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |