SCHEMBL4451807

SCHEMBL4451807

O=C(O)CCCCCOc1ccc(-c2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.51
PPARG P37231 2/20 0.47
FFAR4 Q5NUL3 4/20 0.46
FFAR1 O14842 3/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
FABP3 P05413 1/20 0.45
FABP4 P15090 1/20 0.45
ACLY P53396 1/20 0.45
LTB4R Q15722 2/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44
SCN5A Q14524 1/20 0.44
KMO O15229 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
PPARA Q07869 1/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449795 0.87 FFAR1 (0.49) RAB9APPARGFFAR4FFAR1MAPT
SCHEMBL10382178 0.83 RAB9A (0.70) RAB9AFFAR1MAPTTDP1ALDH1A1
SCHEMBL10381113 0.83 RAB9A (0.70) RAB9AFFAR1MAPTTDP1ALDH1A1
SCHEMBL10381793 0.81 RAB9A (0.72) RAB9AFFAR1MAPTTDP1ALDH1A1
SCHEMBL5339875 0.81 LMNA (0.49) RAB9APPARGTDP1LTB4RTHRA
SCHEMBL20230373 0.81 PPARG (0.68) RAB9APPARGFFAR4FFAR1MAPT
SCHEMBL13244187 0.81 RAB9A (0.56) RAB9APPARGMAPTTDP1LTB4R
SCHEMBL11267671 0.81 ACLY (0.54) RAB9APPARGFFAR4FFAR1MAPT
SCHEMBL20231597 0.80 PPARG (0.49) RAB9APPARGMAPTTDP1FABP3
SCHEMBL9322243 0.78 MEN1 (0.55) RAB9AMAPTTDP1FABP3LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed