SCHEMBL4453745

SCHEMBL4453745

[CH2]C[Zr](OCCl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.35
HTR2A P28223 1/20 0.32
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451821 0.76 HTR2A (0.34) HTR6HTR2A
SCHEMBL939102 0.72 RET (0.37) HTR6HTR2ASIGMAR1
SCHEMBL9220624 0.71 SIGMAR1 (0.36) HTR6HTR2ASIGMAR1
SCHEMBL8677599 0.70 HTR2A (0.34) HTR6HTR2ASIGMAR1
SCHEMBL9064184 0.70 HTR2A (0.35) HTR6HTR2A
Ethylene SCHEMBL2231954 0.70 HTR2A (0.35) HTR6HTR2A
SCHEMBL137961 0.69 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL550007 0.69 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL5859434 0.68 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL6855151 0.68 SIGMAR1 (0.37) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-20040106738-A1 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-06-03 US disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed