Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963055 | 0.82 | BLM (0.50) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5197222 | 0.82 | BLM (0.50) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5365631 | 0.81 | PPARA (0.49) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL4451916 | 0.77 | PPARA (0.46) | PPARAPPARGMAPTPPARDALDH1A1 | |
| SCHEMBL6396442 | 0.75 | PPARA (0.48) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL7777170 | 0.74 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL6387462 | 0.74 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL8679105 | 0.72 | ALDH1A1 (0.38) | THRBTHRAALDH1A1 | |
| SCHEMBL3729766 | 0.71 | SMN1; SMN2 (0.44) | PPARAPPARGMAPTPPARDALDH1A1 | |
| SCHEMBL5142183 | 0.71 | THRA (0.46) | PPARAPPARGTHRBMAPTTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309720-B2 | 2-ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | ASTRAZENECA AB (SE) | 2007-12-18 | — | — | US | disclosed |
| US-20060178432-A1 | 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | ASTRAZENECA AB (SE) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178432-A1 | 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | LIPC, PNLIP, CPT1A | PPARA 34/4885PPARG 72/4885THRB 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.