Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350338 | 0.87 | CYP2C9 (0.60) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL12167909 | 0.85 | CYP2C9 (0.46) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL10255978 | 0.82 | GABBR2 (0.53) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL11082974 | 0.81 | CYP2C9 (0.42) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL30699923 | 0.81 | CYP2C19 (0.51) | CYP2C19LMNAPOLBL3MBTL1EPHX1 | |
| SCHEMBL4462528 | 0.81 | EPHX1 (0.42) | GABBR2GABBR1LMNAEPHX1GAA | |
| SCHEMBL23564521 | 0.81 | FFAR2 (0.48) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL27515059 | 0.81 | FFAR2 (0.48) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL523877 | 0.80 | GABBR2 (0.59) | CYP2C9KMT2ACYP2C19MEN1CYP2D6 | |
| SCHEMBL3353282 | 0.80 | EPHX1 (0.63) | CYP2C19CYP2D6GABBR2GABBR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | CONSEJO SUPERIOR DE (ES) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298781-A1 | COMPOUNDS FOR THE INHIBITION OF APOPTOSIS | BAX, BCL2, CASP3 | CYP2C9 3604/4885KMT2A 4770/4885CYP2C19 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.