SCHEMBL4453076

SCHEMBL4453076

Fc1c(Cl)c(F)c(Cl)c(F)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589276 0.91 CES2 (0.36) CES2CES1
SCHEMBL4449502 0.91 CES2 (0.36) CES2CES1
SCHEMBL5848856 0.89 CES2 (0.33) CES2CES1
SCHEMBL4345041 0.89 CES2 (0.33) CES2CES1
SCHEMBL7214722 0.84 CES2 (0.38) CES2CES1
SCHEMBL219009 0.84 CES2 (0.38) CES2CES1
SCHEMBL1756500 0.84 CES2 (0.38) CES2CES1
Magnesium SCHEMBL30578300 0.80 CES2 (0.36) CES2CES1
SCHEMBL1942159 0.80 CES2 (0.36) CES2CES1
SCHEMBL13170369 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143983-B Preparation method of perfluoropolyether compound 湖南天氟新材料有限公司 2025-02-11 CN claimed
CN-119143983-A Preparation method of perfluoropolyether compound 湖南天氟新材料有限公司 2024-12-17 CN claimed
CN-105130744-A Method for synthesizing 1,3,5-trichloro-2,4,6-trifluorobenzene from 2,4-difluoro-3,5-dichloronitrobenzene ZHEJIANG LINJIANG CHEMICAL CO LTD 2015-12-09 CN claimed
US-7595426-B2 Method for the production of 1,3,5-trifluoro-2,4,6-trichlorobenzene from fluorobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2009-09-29 US claimed
US-20080214878-A1 Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives BASF AKTIENGESELLSCHAFT (DE) 2008-09-04 US claimed
EP-1874715-A1 METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2008-01-09 EP claimed
WO-2006111583-A1 METHOD FOR THE PRODUCTION OF 1,3,5-TRIFLUORO-2,4,6-TRICHLOROBENZENE FROM FLUOROBENZENE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2006-10-26 WO claimed
EP-4363409-B1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2025-06-11 EP disclosed
CN-119143983-B Preparation method of perfluoropolyether compound 湖南天氟新材料有限公司 2025-02-11 CN disclosed
CN-119143983-A Preparation method of perfluoropolyether compound 湖南天氟新材料有限公司 2024-12-17 CN disclosed
US-20240308970-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2024-09-19 US disclosed
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP disclosed
WO-2023274993-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2023-01-05 WO disclosed
US-5283378-A Process for the dechlorination and/or debromination of fluorine-and chlorine- and/or bromine-containing aromatic compounds BAYER AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed
EP-0481317-A2 Method for dechlorination and/or debromination of aromatic compounds containing fluorine with chlorine and/or bromine BAYER AG (DE) 1992-04-22 EP disclosed
EP-0460639-A1 Process for producing 3,5-difluoroaniline and derivative thereof SDS Biotech K.K. (JP) 1991-12-11 EP disclosed
EP-0394644-A2 Halobenzene derivatives BAYER AG (DE) 1990-10-31 EP disclosed
US-4734503-A Catalytic transhalogenation of haloaromatics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-29 US disclosed
EP-0233035-A1 Catalytic transhalogenation of haloaromatics E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-19 EP disclosed
US-3953789-A Method of polarizing nuclei INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214878-A1 Method For The Production Of 1,3,5-Trifluoro-2,4,6-Trichlorobenzene From Fluorobenzene Derivatives FLNB, AFF1, AFF2 CES2 52/4885CES1 324/4885
US-20240308970-A1 METHOD FOR PRODUCING ALKYLENE OXIDES AOC2, SCO2, AOC3 CES2 970/4885CES1 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.