SCHEMBL5848856

SCHEMBL5848856

Fc1c(Cl)c(Cl)c(F)c(Cl)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1756500 0.95 CES2 (0.38) CES2CES1
SCHEMBL4449502 0.91 CES2 (0.36) CES2CES1
SCHEMBL4453076 0.89 CES2 (0.33) CES2CES1
SCHEMBL1756501 0.84 CES2 (0.38) CES2CES1
SCHEMBL1756530 0.84 CES2 (0.38) CES2CES1
SCHEMBL10589276 0.80 CES2 (0.36) CES2CES1
SCHEMBL1756525 0.80 CES2 (0.43) CES2CES1
SCHEMBL18568549 0.80
SCHEMBL4345041 0.78 CES2 (0.33) CES2CES1
SCHEMBL8025114 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7148383-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2006-12-12 US disclosed
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same LESLIE THOMAS M 2005-10-27 US disclosed
US-6933412-B2 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED (US) 2005-08-23 US disclosed
US-20040044251-A1 Low loss high refractive index vinyl sulfide compounds and method of making same CORNING INCORPORATED 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240060-A1 Low loss high refractive index vinyl sulfide compounds and method of making same CRY2, SOS2, CRYZ CES2 3673/4885CES1 3199/4885
US-20040044251-A1 Low loss high refractive index vinyl sulfide compounds and method of making same SOS2, CRY2, PER2 CES2 3583/4885CES1 3625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.