Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 8/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13722986 | 0.74 | KDM4E (0.42) | XDHMAP3K5KDM4EASPHKDM8 | |
| SCHEMBL13004322 | 0.73 | XDH (0.48) | XDHKDM4EASPHKDM8 | |
| SCHEMBL4446698 | 0.72 | XDH (0.48) | XDHKDM4E | |
| SCHEMBL16313328 | 0.71 | KDM4E (0.40) | XDHMAP3K5SLC22A12KDM4EASPH | |
| SCHEMBL14184585 | 0.70 | XDH (0.45) | XDH | |
| SCHEMBL13723419 | 0.70 | KDM4E (0.45) | XDHMAP3K5SLC22A12KDM4EASPH | |
| SCHEMBL3586838 | 0.68 | XDH (0.41) | XDHSLC22A12KDM4E | |
| SCHEMBL14384228 | 0.67 | XDH (0.52) | XDHKDM4E | |
| SCHEMBL22245628 | 0.64 | KDM4E (0.56) | KDM4EASPHKDM8 | |
| SCHEMBL26036572 | 0.64 | KMO (0.62) | KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992361-B1 | Remedy or preventive for digestive ulcer | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1992361-A1 | REMEDY OR PREVENTIVE FOR DIGESTIVE ULCER | Astellas Pharma Inc. (JP) | 2008-11-19 | — | — | EP | disclosed |