Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13004322 | 0.84 | XDH (0.48) | KDM4EASPHKDM8RXFP1XDH | |
| SCHEMBL16313328 | 0.82 | KDM4E (0.40) | KDM4EASPHKDM8MAP3K5XDH | |
| SCHEMBL13723419 | 0.80 | KDM4E (0.45) | KDM4EASPHKDM8KMT2AMAP3K5 | |
| SCHEMBL14184585 | 0.78 | XDH (0.45) | XDH | |
| SCHEMBL14384228 | 0.78 | XDH (0.52) | KDM4EKMT2AXDH | |
| SCHEMBL4453345 | 0.74 | XDH (0.35) | KDM4EASPHKDM8MAP3K5XDH | |
| SCHEMBL22245628 | 0.73 | KDM4E (0.56) | KDM4EASPHKDM8KMT2ATDP1 | |
| SCHEMBL26036572 | 0.73 | KMO (0.62) | KDM4EASPHKDM8 | |
| SCHEMBL2657725 | 0.70 | CYP11B2 (0.45) | KDM4ERXFP1HDAC1TDP1 | |
| SCHEMBL13545903 | 0.69 | KDM4E (0.51) | KDM4EKMT2AXDHTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783116-B1 | 2-PHENYLPYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2009-08-26 | — | — | EP | disclosed |