SCHEMBL4453481

SCHEMBL4453481

Clc1cccc(-c2c(Cl)c(Cl)cc(Cl)c2Cl)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.41
IDO1 P14902 1/20 0.41
TSHR P16473 1/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAOA P21397 1/20 0.39
MAPK1 P28482 1/20 0.39
ADRA1A P35348 1/20 0.39
SCN4A P35499 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
PDE3A Q14432 1/20 0.39
SCN5A Q14524 1/20 0.39
SCN9A Q15858 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
SCN10A Q9Y5Y9 1/20 0.39
PNMT P11086 1/20 0.38
MET P08581 1/20 0.38
NUDT1 P36639 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450215 0.86 CYP3A4 (0.42) NOTUMIDO1TSHRCYP3A4CYP2D6
SCHEMBL29624838 0.85 TSHR (0.44) NOTUMIDO1TSHRCYP2D6MAOA
SCHEMBL2229304 0.85 TSHR (0.44) NOTUMIDO1TSHRCYP2D6MAOA
SCHEMBL4447012 0.83 NOTUM (0.42) NOTUMIDO1TSHRCYP2D6MAOA
SCHEMBL28988428 0.83 NOTUM (0.42) NOTUMIDO1TSHRCYP2D6MAOA
SCHEMBL29682856 0.83 CYP2A6 (0.48) NOTUMIDO1TSHRCYP3A4ALDH1A1
SCHEMBL4449783 0.83 CYP2A6 (0.48) NOTUMIDO1TSHRCYP3A4ALDH1A1
SCHEMBL30621941 0.83 NOTUM (0.42) NOTUMIDO1TSHRCYP2D6MAOA
SCHEMBL4456270 0.82 TSHR (0.46) NOTUMIDO1TSHRCYP3A4CYP2D6
SCHEMBL4456481 0.81 ALDH1A1 (0.43) NOTUMIDO1TSHRCYP2D6MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
CN-222441970-U Electrical device 米沃奇电动工具公司 2025-02-07 CN disclosed
CN-111886057-B Input device for electronic system 谷歌有限责任公司 2024-09-20 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116487232-A Surge protector module and assembly 雷凯浦知识产权发展有限公司 2023-07-25 CN disclosed
CN-116470866-A Power amplifier module and system including electromagnetic bandgap isolation array 恩智浦美国有限公司 2023-07-21 CN disclosed
CN-112968328-B Wired communication device and system for mobile robot 苏州玖物互通智能科技股份有限公司 2022-05-31 CN disclosed
CN-216318797-U Cosmetic comb 深圳市创通电子器械有限公司 2022-04-19 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed