SCHEMBL4450215

SCHEMBL4450215

Clc1cccc(-c2c(Cl)cc(Cl)c(Cl)c2Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
NOTUM Q6P988 2/20 0.39
IDO1 P14902 1/20 0.39
AHR P35869 3/20 0.39
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.37
CYP2D6 P10635 1/20 0.37
MAOA P21397 1/20 0.37
ADRA1A P35348 1/20 0.37
SCN4A P35499 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
PDE3A Q14432 1/20 0.37
SCN5A Q14524 1/20 0.37
SCN9A Q15858 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37
SCN10A Q9Y5Y9 1/20 0.37
MET P08581 1/20 0.36
NUDT1 P36639 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453481 0.86 NOTUM (0.41) CYP3A4NOTUMIDO1AHRTSHR
SCHEMBL30621943 0.84 CYP2A6 (0.44) CYP3A4IDO1AHRTSHRMAPK1
SCHEMBL4453386 0.84 CYP2A6 (0.44) CYP3A4IDO1AHRTSHRMAPK1
SCHEMBL4456481 0.82 ALDH1A1 (0.43) NOTUMIDO1AHRTSHRMAPK1
SCHEMBL4449569 0.82 AHR (0.58) CYP3A4AHRTSHRMAPK1ALDH1A1
SCHEMBL2229304 0.81 TSHR (0.44) NOTUMIDO1TSHRMAPK1CYP2D6
SCHEMBL29624838 0.81 TSHR (0.44) NOTUMIDO1TSHRMAPK1CYP2D6
SCHEMBL11760120 0.80 CYP3A4 (0.50) CYP3A4AHRTSHRMAPK1ALDH1A1
SCHEMBL4448496 0.79 CYP3A4 (0.48) CYP3A4AHRTSHRMAPK1PNMT
SCHEMBL28988428 0.79 NOTUM (0.42) NOTUMIDO1TSHRMAPK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234496-B Low-humidity-sensitivity regenerated PC/PET composite material and preparation method thereof 宁波坚锋新材料有限公司 2022-05-03 CN claimed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
WO-2026086362-A1 SAR TEST METHOD AND ELECTRONIC DEVICE 荣耀终端股份有限公司 2026-04-30 WO disclosed
US-20260094839-A1 COMPOSITION FOR ELECTRODE FORMATION AND ADDITIVE NISSAN CHEMICAL CORPORATION (JP) 2026-04-02 US disclosed
EP-4651238-A1 COMPOSITION FOR ELECTRODE FORMATION AND ADDITIVE Nissan Chemical Corporation (JP) 2025-11-19 EP disclosed
CN-119268898-A Dynamic torque sensor 广州市斯巴拓电子科技有限公司 2025-01-07 CN disclosed
CN-118500217-A Wireless detonator of digital electronic detonator 兰陵金顺爆破工程有限公司 2024-08-16 CN disclosed
US-20230330725-A1 VOLATILIZATION AND OXIDATION OF ORGANIC WASTE NATIONAL BANK OF CANADA (CA) 2023-10-19 US disclosed
CN-116300170-A Display device 乐金显示有限公司 2023-06-23 CN disclosed
CN-111701144-B Systems and methods for phototherapy modulation of nitric oxide 诺欧生物有限责任公司 2023-03-21 CN disclosed
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP disclosed
US-20090269857-A1 Instruments for detecting low-molecular weight substance FUJIKURA KASEI CO., LTD. (JP) 2009-10-29 US disclosed
US-20050148097-A1 Instruments for detecting low-molecular weight substance ENBIOTEC LABORATORIES C., LTD. (JP) 2005-07-07 US disclosed
EP-1489420-A1 INSTRUMENTS FOR DETECTING LOW-MOLECULAR WEIGHT SUBSTANCE Enbiotec Laboratories Co., Ltd. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260094839-A1 COMPOSITION FOR ELECTRODE FORMATION AND ADDITIVE SET, CACNA2D4, CACNA2D1 CYP3A4 1843/4885NOTUM 4204/4885IDO1 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.