SCHEMBL4453780

SCHEMBL4453780

C=CC(Cl)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.43
ESR2 Q92731 6/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
MAPT P10636 5/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 4/20 0.39
CYP3A4 P08684 3/20 0.39
LMNA P02545 2/20 0.38
NFKB1 P19838 2/20 0.38
HIF1A Q16665 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034832 0.76 ALDH1A1 (0.52) ALDH1A1TDP1TSHR
SCHEMBL6473743 0.76 ESR1 (0.43) ESR1ESR2PDCD1CD274MAPT
SCHEMBL31518927 0.76 XDH (0.46) MAPTKDM4EALDH1A1HPGDALOX15
Benzene SCHEMBL28136546 0.75 TSHR (0.50) MAPTKDM4EALDH1A1HPGDALOX15
SCHEMBL5461559 0.75 MAPT (0.56) ESR1ESR2PDCD1CD274MAPT
SCHEMBL109223 0.75 TSHR (0.50) MAPTKDM4EALDH1A1HPGDALOX15
SCHEMBL6158874 0.74 ALDH1A1 (0.38) ALDH1A1CYP2C19ALDH5A1ABAT
Hydrochloric Acid SCHEMBL11666238 0.73 TSHR (0.48) MAPTKDM4EALDH1A1HPGDALOX15
Ammonia Solution, Strong SCHEMBL9691228 0.73 TSHR (0.48) MAPTKDM4EALDH1A1HPGDALOX15
SCHEMBL387119 0.73 ESR1 (0.44) ESR1ESR2PDCD1CD274MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109564213-A Detecting microbial wound infection 西诺福有限公司 2019-04-02 CN disclosed
US-20090169955-A1 MEMBRANE FOR FUEL CELLS, CONTAINING POLYMERS COMPRISING PHOSPHONIC ACID GROUPS AND/OR SULFONIC ACID GROUPS, MEMBRANE UNITS AND THE USE THEREOF IN FUEL CELLS BASF FUEL CELL GMBH (DE) 2009-07-02 US disclosed