Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13959332 | 0.91 | PIM1 (0.41) | PIM1PIM3PIM2ADORA2AADORA1 | |
| Trifluoroacetic Acid SCHEMBL4451796 | 0.80 | MEN1 (0.46) | FFAR4HTR2CCASP6MAPK13MAPK9 | |
| SCHEMBL4458994 | 0.76 | HTT (0.48) | — | |
| SCHEMBL4458992 | 0.74 | FFAR4 (0.35) | FFAR4TNFRSF1AADORA2AADORA1HDAC8 | |
| SCHEMBL4457904 | 0.73 | PIM1 (0.44) | FFAR4PIM1PIM3PIM2HRH4 | |
| Trifluoroacetic Acid SCHEMBL28665355 | 0.72 | CDK4 (0.43) | HRH4HRH3HTR2CCNR2 | |
| SCHEMBL13959317 | 0.71 | MEN1 (0.53) | PIM1PIM3PIM2HTR2CMAPK13 | |
| SCHEMBL4454107 | 0.70 | IRAK4 (0.39) | FFAR4 | |
| SCHEMBL3580316 | 0.70 | PTGS2 (0.43) | ADORA1HRH4HTR2C | |
| SCHEMBL4464087 | 0.69 | PTGS2 (0.43) | TNFRSF1AADORA2AADORA1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144473-A1 | ANTIFUNGAL COMBINATION THERAPY | F2G LIMITED (GB) | 2009-12-03 | — | — | WO | claimed |